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KMID : 0861019990140020023
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Korea Journal of Herbology
1999 Volume.14 No. 2 p.23 ~ p.32
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Study on anti - oxidatve effects of Ginseng Radix with other combined
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朴時興/Park, Si-Heung
康秉秀/朴涌基/Kang, Byung-Soo/Park, Yong-Ki
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Abstract
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This study was carried out in order to investigate the anti-oxidant effect of main tonic medicine, Ginseng Radix with combination of other well-known herb medicines such as Rehmammiae Radix Preparat, Astragali, Poria, Aconiti lateralis Preparata Radix, Gecko and Bupleuri Radix.
These herbs were mixed with Ginseng Radix to measure inhibitory activity lipid peroxidation of linoleic acid mixture and rat liver and hydrogen-giving-temper effect by DPPH.
The study showed the following valuable results.
1. In inhibitory activity of water extract against lipid peroxidation of linoleic acid mixture, Ginseng Radix-Gecko compound herbal medicine showed the highest anti-oxidant activity. Ginseng Radix -Rehmammiae Radix Preparat compound herbal medicine showed the lowest anti-oxidant activity when compared with the examined samples.
2. In inhibitory activity of water extract against lipid peroxidation of rat liver, Ginseng Radix-Gecko showed the highest anti-oxidant activity. Ginseng Radix-Rehmammiae Radix Preparat showed the lowest anti-oxidant activity.
3. In hydrogen-giving-temper effect of water extract by DPPH, Ginseng Radix-Gecko compound herbal medicine showed the highest anti-oxidant activity.
4. In the linoleic acid mixture, Ginseng Radix-Gecko compound herbal medicine showed the highest anti-oxidant activity in Butanol fraction.
5. In the lipid peroxidation of rat liver, Ginseng Radix-Gecko compound herbal medicine showed the highest anti-oxidant activity in Butanol fraction.
6. In hydrogen-giving-temper effect of water extract by DPPH, Ginseng Radix-Gecko compound herbal medicine showed the highest anti-oxidant activity in Butanol fraction.
From the above results, it was concluded as follows.
All the six compound herbal medicine including Ginseng Radix showed the anti-oxidant activity. Especially, Ginseng Radix-Gecko compound herbal medicine showed the highest anti-oxidant activity among them.
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